A dopey, naïve man in his thirties brings chaos to the lives of his three sisters.

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Candid, laid-back, spontaneous, dressed in floppy shorts and Crocs with hippie hair and beard, Ned (Paul Rudd) goes to jaded, pretentious New-York, where his naïveté makes the locals think he's mentally handicapped. At 35, he's never had a stable job and his good heart leads him to prison. Dumped by his girlfriend on his release, he's taken in by his three sisters: earth mother Liz who's married to an unpleasant English documentary filmmaker; the ambitious journalist Miranda; and Natalie, an artist who is still in search of herself. But the blunt Ned soon reveals the disorder lying underneath the surface of his sisters' seemingly together lives...

Jesse Peretz takes a humorous look at the pretentions of New York yuppies, who give stupid names to their children (River, Echo) in reference to a nature they never experience, who make them play the Shehnai because everything from India is sacred, who feel guilty because they are heterosexual... Western hypocrisy is criticized, but not enough, because order returns once the three sisters realize that honesty pays. The politically correct ending somewhat defuses this charming satire.