Tom Tykwer, Andy and Lana Wachowski tell six stories stretched out over 500 years, each one having an impact on the others.

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Sailing the Pacific in 1849 and discovering slavery there, Adam Ewin writes everything in his journal, which is read by Robert Frobisher, a penniless musician who soon finds work with composer Vyvyan Ayrs in 1932. Frobisher tells the story to his lover Rufus Sixsmiths in letters he sends to him until the end of his life. In 1975, Sixsmiths, now a scientist, is assassinated as he delivers a secret file to Luisa Rey, a journalist investigating a dangerous and confidential nuclear project. In 2012, editor Timothy Cavendish has possession of Rey's manuscript, but he is held prisoner in an institution so that the document will never be published. In Korea in 2144, a totalitarian state manufactures female clones. One of them, Sonmi 451, develops a conscience and calls for rebellion...

In their adaptation of David Mitchen's novel, Tom Tykwer (Perfum), Andy and Lana Wachowski (Matrix) strive to show how every action, god or bad, has an impact on the actions of others and that every meeting affects the future. Thanks, we knew that! Three hours later, the audience leaves the theater exhausted by the complex intrigue of this grandiloquent spectacle and the multiple roles of the actors.